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Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
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Rous Sarcoma Virus (RSV) and Cancer01:03

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Bones of the Lower Limb: Femur and Patella01:16

Bones of the Lower Limb: Femur and Patella

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Related Experiment Video

Updated: May 27, 2026

A Syngeneic Orthotopic Osteosarcoma Sprague Dawley Rat Model with Amputation to Control Metastasis Rate
07:31

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Published on: May 3, 2021

Osteosarcoma in a woma python (Aspidites ramsayi).

M L Cowan1, D J Monks, S R Raidal

  • 1Brisbane Bird and Exotics Veterinary Service, Macgregor, Queensland, Australia. melinda@bbevs.com

Australian Veterinary Journal
|November 23, 2011
PubMed
Summary
This summary is machine-generated.

A rare case of axial skeleton osteosarcoma was diagnosed in an 18-month-old woma python. The study details the progressive growth and ulceration of a subcutaneous mass, leading to a low-grade osteosarcoma diagnosis.

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Last Updated: May 27, 2026

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Area of Science:

  • Herpetology
  • Veterinary Pathology
  • Comparative Oncology

Background:

  • Osteosarcoma is a primary bone malignancy typically affecting long bones in mammals.
  • Axial skeleton involvement is uncommon, particularly in non-mammalian species.
  • This case presents a unique instance of osteosarcoma in a reptile.

Observation:

  • An 18-month-old woma python presented with a progressive subcutaneous mass over the costal arches.
  • The mass enlarged over five months, becoming ulcerated and invasive.
  • Diagnostic imaging and histopathology were performed on a punch biopsy sample.

Findings:

  • Histopathological examination confirmed a diagnosis of low-grade osteosarcoma.
  • The tumor demonstrated invasive characteristics into surrounding tissues.
  • This represents a rare occurrence of osteosarcoma in the axial skeleton of a woma python.

Implications:

  • This case expands the known spectrum of neoplastic diseases in captive reptiles.
  • Understanding osteosarcoma in exotic species aids in comparative oncology research.
  • Early detection and diagnosis are crucial for managing similar presentations in veterinary practice.