Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association of stage of diabetic retinopathy on intraocular pressure.

Digital journal of ophthalmology : DJO·2026
Same author

Visual Electrophysiology for the Diagnosis of Glaucoma: A Report by the American Academy of Ophthalmology.

Ophthalmology·2026
Same author

Are We Treating Pressure or Treating Patients?

JAMA ophthalmology·2026
Same author

Comparison of Visual Field Fluctuation Between Myopic and Emmetropic Glaucoma Patients.

Journal of ophthalmology·2025
Same author

Faecal contamination determines bacterial assemblages over natural environmental parameters within intermittently opened and closed lagoons (ICOLLs) during high rainfall.

Water research·2024
Same author

Reply.

Ophthalmology·2024
Same journal

Tonographic outflow facility and intraocular pressure after standalone OMNI surgery.

Journal of glaucoma·2026
Same journal

Factors Associated With Retinal Nerve Fiber Layer Asymmetry in Primary Open-Angle Glaucoma Among Individuals of African Ancestry.

Journal of glaucoma·2026
Same journal

Haploinsufficiency of PITX2 in Four Chinese Families with Axenfeld-Rieger Syndrome.

Journal of glaucoma·2026
Same journal

Intraocular Pressure-Lowering Effect of Omidenepag Isopropyl as a Predictor for the Efficacy of Laser Trabeculoplasty.

Journal of glaucoma·2026
Same journal

Comparative Outcomes Between Micropulse and Slow-Coagulation Transscleral Cyclophotocoagulation in Eyes With Good Visual Acuity.

Journal of glaucoma·2026
Same journal

Machine Learning With Optical Coherence Tomography for Glaucoma Diagnosis.

Journal of glaucoma·2026
See all related articles

Related Experiment Video

Updated: May 27, 2026

Using Retinal Imaging to Study Dementia
09:17

Using Retinal Imaging to Study Dementia

Published on: November 6, 2017

Correlation between macular thickness and glaucomatous visual fields.

Whitney Boling1, Darrell WuDunn, Louis B Cantor

  • 1Department of Ophthalmology, Eugene and Marilyn Glick Eye Institute, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA.

Journal of Glaucoma
|November 23, 2011
PubMed
Summary
This summary is machine-generated.

This study found predictable structural links between macular thickness and visual field defects in glaucoma patients. Optical coherence tomography (OCT) macular scans can aid in glaucoma diagnosis and management.

Related Experiment Videos

Last Updated: May 27, 2026

Using Retinal Imaging to Study Dementia
09:17

Using Retinal Imaging to Study Dementia

Published on: November 6, 2017

Area of Science:

  • Ophthalmology
  • Medical Imaging

Background:

  • Glaucoma is a leading cause of irreversible blindness.
  • Early detection and monitoring of glaucoma are crucial for effective management.
  • Visual field (VF) defects and retinal nerve fiber layer thinning are key indicators of glaucoma progression.

Purpose of the Study:

  • To investigate the existence of predictable structural relationships between macular thickness parameters and corresponding visual field defects.
  • To determine if macular thickness measurements from optical coherence tomography (OCT) correlate with specific patterns of visual field loss in glaucoma.

Main Methods:

  • Retrospective analysis of optical coherence tomography (OCT) macular scans and automated visual fields (VFs) from 127 glaucoma patients.
  • Recorded macular scan parameters included superior and inferior inner and outer sectors.
  • Calculated mean threshold sensitivities for grouped VF points corresponding to macular regions and analyzed correlations using Spearman correlation.

Main Results:

  • Statistically significant structural relationships were observed between macular thickness parameters and anatomically related VF defects.
  • Strongest correlations identified between inferior outer macula and superior outer VF, inferior inner macula and superior inner VF, superior inner macula and inferior inner VF, and superior outer macula and inferior outer VF.

Conclusions:

  • A predictable and significant structural relationship exists between macular thickness and visual field defects in glaucoma.
  • Macular OCT scans warrant further investigation and careful consideration in the diagnosis and management of glaucoma.
  • These findings support the utility of OCT in assessing glaucoma severity and progression.