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En bloc esophagectomy: the first 100 patients
1New York Hospital-Cornell Medical Center, Division of Cardiothoracic Surgery, New York.
Hepato-Gastroenterology
|August 1, 1990
Summary
En bloc esophagectomy for esophageal carcinoma demonstrated no cancer recurrence after 3 years in a study of 111 patients. This surgical approach offers potential curative outcomes, even for patients with unfavorable prognostic factors.
Area of Science:
- Oncology
- Surgical Oncology
- Gastrointestinal Surgery
Background:
- Esophageal carcinoma presents a significant challenge in surgical oncology.
- En bloc esophagectomy is a complex procedure for managing esophageal cancer.
Purpose of the Study:
- To evaluate the outcomes of en bloc esophagectomy for esophageal carcinoma.
- To assess the efficacy and safety of this surgical technique.
Main Methods:
- Retrospective analysis of 251 patients with esophageal carcinoma between 1969 and 1984.
- Detailed description of the en bloc esophagectomy technique for 111 patients.
Main Results:
- Hospital mortality was 11% (12/111) with 49 reported complications.
- No cancer recurrences were observed beyond 3 years post-operation.
- Five-year absolute survival rates varied significantly based on tumor-node-metastasis (TNM) staging (W1N0: 55%, W1N1: 29%, W2N0: 15%, W1/W2N2: 8%).
Conclusions:
- En bloc resection for esophageal carcinoma is feasible with acceptable mortality and morbidity.
- The procedure holds potential for curative treatment in a subset of patients, including those with adverse prognostic indicators.