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Should multivisceral transplantation be considered in patients colonized with multidrug-resistant Pseudomonas
Diana F Florescu1, Wendy Grant, Jean F Botha
1Transplant Infectious Diseases Program, Infectious Diseases Division, University of Nebraska Medical Center, Omaha, Nebraska NE 68198-5400, USA. dflorescu@unmc.edu
Insights
This study details two multivisceral transplantations in a child with multidrug-resistant Pseudomonas aeruginosa. It highlights challenges and management strategies for transplanting patients colonized with these resistant bacteria.
Area of Science:
- Organ transplantation
- Infectious diseases
- Microbiology
Background:
- Multivisceral transplantation is a complex procedure.
- Colonization with multidrug-resistant Pseudomonas aeruginosa poses significant risks in transplant candidates.
Observation:
- Two subsequent liver-small bowel-pancreas-kidney transplantations were performed in a pediatric patient.
- The patient was colonized with multidrug-resistant Pseudomonas aeruginosa.
Findings:
- The report discusses the challenges and potential consequences of transplanting patients colonized with multidrug-resistant Pseudomonas spp.
- Perioperative and postoperative management strategies are detailed.
Implications:
- This case highlights the need for careful consideration and management protocols for transplanting patients with multidrug-resistant organisms.
- It informs clinical decision-making and patient care in complex transplant scenarios.
Abstract:
This report describes two subsequent liver-small bowel-pancreas-kidney (multivisceral) transplantations in a child colonized with multidrug-resistant Pseudomonas aeruginosa. We discuss the dilemma concerning the transplantation of patients colonized with multidrug-resistant Pseudomonas spp., its potential consequences, and the peri and postoperative management of these patients.
