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Published on: April 22, 2019
Pretreatment thrombocytosis: a prognostic marker for oral squamous cell carcinoma?
Steffen Kargus1, Franz E Weber, Heinz T Luebbers
1Department of Craniomaxillofacial and Oral Surgery, University Hospital Zurich, Frauenklinikstr. 24, 8091, Zurich, Switzerland.
Purpose:
Thrombocytosis associated with poorer prognoses seems to be a frequent preoperative finding in different kind of cancers. The aim of the present study was to evaluate whether thrombocytosis can be used as a prognostic marker for oral squamous cell carcinoma (SCC).
Methods:
Altogether, 288 patients with oral SCC were considered, as well as all platelet counts between 1 and 5 days prior to surgical treatment, recurrence rate, and lymph node metastasis. The minimum follow-up time was 12 months.
Results:
The mean preoperative thrombocyte score of the patients who received surgery was 259.55 ± 83.8 Tsd/μl; 273 out of 288 patients were in the normal thrombocyte range, and 12 had a thrombocytosis. From 51 patients with recurrence, three were in the thrombocytosis group, and 45 patients with recurrence were in the normal thrombocyte range.
Conclusion:
The present results do not confirm that thrombocytosis can be seen as marker for poor tumor prognosis.
