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Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
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Ambiguity of optical coherence tomography measurements due to rough surface scattering
Y Ashtamker1, V Freilikher, J C Dainty
1Department of Physics, Bar-Ilan University, Ramat Gan 52900, Israel.
Optics Express
|November 24, 2011
Abstract:
Optical coherence tomography (OCT) images are frequently interpreted in terms of layers (for example, of tissue) with the boundary defined by a change in refractive index. Real boundaries are rough compared with the wavelength of light, and in this paper we show that this roughness has to be taken into account in interpreting the images. We give an example of the same OCT image obtained from two quite different objects, one smooth compared to the optical wavelength, and the other rough.

