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Updated: May 27, 2026

Deep Vein Thrombosis Induced by Stasis in Mice Monitored by High Frequency Ultrasonography
Published on: April 13, 2018
Mean platelet volume is increased in patients with deep vein thrombosis
Mehmet Gulcan1, Ercan Varol, Mustafa Etli
1Department of Cardiology, Suleyman Demirel University, Faculty of Medicine, Isparta, Turkey. dr.mgulcan@hotmail.com
Background:
Pulmonary thromboembolism is a serious complication in patients with deep vein thrombosis (DVT). Previous studies have demonstrated that platelet activation occurs in patients with DVT. Mean platelet volume (MPV) is a simple and easy method of assessing platelet function. The aim of this study was to assess the MPV, an indicator of platelet activation in patients with DVT.
Patients And Methods:
The study group consisted of 52 patients with newly diagnosed acute DVT. An age-, gender-, and body mass index-matched control group consisted of 30 healthy volunteers. All patients and control participants underwent ultrasonographic examination. We measured the serum MPV values in patients with DVT and control participants.
Results:
Mean platelet volume was significantly higher among patients with DVT when compared with the control group (8.6 ± 0.8 vs 7.7 ± 0.9 fL, respectively; P < .001).
Conclusion:
We have shown that MPV was significantly elevated in patients with DVT compared to controls.
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