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Determination of the Gas-phase Acidities of Oligopeptides
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Determination of the Gas-phase Acidities of Oligopeptides

Published on: June 24, 2013

2-Pyridone and derivatives: gas-phase acidity, proton affinity, tautomer preference, and leaving group ability

Anna Zhachkina Michelson1, Aaron Petronico, Jeehiun K Lee

  • 1Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, New Brunswick, New Jersey 08901, USA.

The Journal of Organic Chemistry
|November 25, 2011
PubMed

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Carboxylic acid derivatives contain an acyl group attached to a heteroatom such as chlorine, oxygen, or nitrogen. The carbonyl carbon and oxygen are both sp2-hybridized with an unhybridized p orbital.
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