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Updated: May 27, 2026
05:51
Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain
Published on: July 24, 2016
Neuroinfectious diseases in pregnancy
Kelly Jo Baldwin1, Karen L Roos
1Department of Neurology, West Virginia University, Morgantown, West Virginia 26506, USA. kbaldwin@hsc.wvu.edu
Seminars in Neurology
|November 25, 2011
Summary
Pregnancy weakens T-cell immunity, increasing infection risk. Severe maternal infections, especially herpesvirus, can cause fetal loss and congenital issues.
Area of Science:
- Neuroscience
- Immunology
- Maternal-Fetal Medicine
Background:
- Pregnancy naturally suppresses T-cell immunity.
- This immune modulation increases susceptibility to infections.
- Certain infections pose risks to both mother and fetus.
Observation:
- Herpesvirus infections during pregnancy can lead to severe outcomes.
- Neurologic infectious diseases present unique challenges in pregnant individuals.
- Intrauterine infections may result in congenital abnormalities.
Findings:
- Review focuses on neurologic infections in pregnancy.
- Examines safety of antimicrobial treatments during gestation.
- Details congenital and neonatal sequelae of maternal infections.
Implications:
- Highlights risks of specific infections during pregnancy.
- Informs treatment strategies for pregnant women with infections.
- Emphasizes need for monitoring fetal and neonatal health outcomes.
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