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Amphotericin B O-methyl oxime. Synthesis and biological properties
A Czerwiński1, W A König, P Sowiński
1Department of Pharmaceutical Technology and Biochemistry, Technical University of Gdańsk, Poland.
The Journal of Antibiotics
|September 1, 1990
Abstract:
Synthesis and biological properties of amphotericin B O-methyl oxime are described. The presence of an intact hemiketal ring in the antibiotic molecule appeared to be essential for its biological activity.