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Published on: July 10, 2014
Remineralization of early enamel lesions using casein phosphopeptide amorphous calcium Phosphate: an ex-vivo study
Ruchi Vashisht1, Anil Kumar, R Indira
1Department of Conservative Dentistry and Endodontics, Ragas Dental College and Hospital, Chennai, India. dr.ruchivashisht@gmail.com
Objective:
This study aimed at qualitatively evaluating the remineralization potential of casein phosphopeptide amorphous calcium phosphate on artificial early enamel lesions in an ex-vivo scenario by observing the treated tooth surface using a scanning electron microscope (SEM).
Materials And Methods:
This randomized study was conducted on 10 subjects undergoing orthodontic treatment with premolar extraction as part of their treatment. Artificial white lesions were created with the application of 37% phosphoric acid for 20 mins. Teeth were then divided into two groups: one experimental and the other control. Customised orthodontic band with a window was luted with intermediate restorative material in the experimental group whereas in the control group, band without a window was luted. The casein phosphopeptide amorphous calcium phosphate (GC TOOTH MOUSSE) paste was then applied on the window region of the experimental group for 3 mins thrice daily after meals for 14 days, whereas no paste was applied in the control group. After 14 days, teeth were extracted and viewed under an SEM.
Results:
The study groups showed remineralization of the lesions as compared with the control group in most of the samples.
Conclusion:
Casein phophopeptide could significantly remineralize the artificial enamel lesions in vivo.

