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Updated: May 27, 2026

Yeast As a Chassis for Developing Functional Assays to Study Human P53
14:57

Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

Modeling the basal dynamics of p53 system.

Tingzhe Sun1, Weiwei Yang, Jing Liu

  • 1State Key Laboratory of Pharmaceutical Biotechnology, Department of Life Sciences, Nanjing University, Nanjing, Jiangsu Province, People's Republic of China.

Plos One
|November 25, 2011
PubMed
Summary

The p53 protein exhibits spontaneous, asynchronous pulses even without stress, triggered by an excitable mechanism. Cells only respond robustly to severe DNA damage, advancing p53 therapy insights.

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