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Related Concept Videos

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Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
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Endocarditis II: Clinical Features of Infective Endocarditis

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Related Experiment Video

Updated: May 27, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
07:24

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

Fungal endophthalmitis.

Jay Chhablani1

  • 1Shiley Eye Center, University of California, San Diego, 9415 Campus Point Drive, La Jolla, CA 92093, USA. jay.chhablani@gmail.com

Expert Review of Anti-Infective Therapy
|November 26, 2011
PubMed
Summary

Fungal endophthalmitis (FE) is rare but causes vision loss. Prompt diagnosis and antifungal treatment, tailored to the specific fungus, improve outcomes for this serious eye infection.

Area of Science:

  • Ophthalmology
  • Mycology
  • Infectious Diseases

Background:

  • Fungal endophthalmitis (FE) is an uncommon ocular infection with significant visual morbidity.
  • FE can be classified as exogenous or endogenous, with distinct causative agents and clinical presentations.
  • Common fungal pathogens include Candida albicans, Aspergillus niger, and Fusarium solani, depending on the infection's origin.

Purpose of the Study:

  • To review current literature on fungal endophthalmitis.
  • To focus on effective antifungal agents and species-specific management strategies.
  • To discuss the outcomes of various treatment approaches for FE.

Main Methods:

  • Literature review of current research on fungal endophthalmitis.
  • Analysis of clinical features, causative organisms, and treatment modalities.

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Establishing Fungal Entomopathogens as Endophytes: Towards Endophytic Biological Control
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Establishing Fungal Entomopathogens as Endophytes: Towards Endophytic Biological Control

Published on: April 11, 2013

Related Experiment Videos

Last Updated: May 27, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
07:24

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

Establishing Fungal Entomopathogens as Endophytes: Towards Endophytic Biological Control
15:14

Establishing Fungal Entomopathogens as Endophytes: Towards Endophytic Biological Control

Published on: April 11, 2013

  • Evaluation of species-specific management and prognostic factors.

    • Main Results:

    • Clinical features of FE vary based on fungal virulence and infection route.
    • Systemic antifungal therapy, potentially combined with intravitreal agents, is the recommended treatment.
    • Prognosis is influenced by pathogen virulence, extent of ocular involvement, and timeliness of intervention.

    Conclusions:

    • Early diagnosis and prompt, targeted antifungal therapy are crucial for reducing vision loss in FE.
    • Management strategies should be adapted to the specific fungal species involved.
    • Understanding species-specific characteristics is key to optimizing outcomes in fungal endophthalmitis.