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Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
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Sinjini Biswas1, Andrew E Ajani

  • 1Department of Cardiology, Royal Melbourne Hospital, Parkville, VIC 3050, Australia. sinjini.biswas@mh.org.au

Cardiovascular Revascularization Medicine : Including Molecular Interventions
|November 26, 2011
PubMed

Insights

Recent myocardial infarction (MI) increases stroke risk. Intravenous thrombolysis, a stroke treatment, was safely administered to a patient with recent MI, challenging contraindications.

Area of Science:

  • Cardiology
  • Neurology
  • Stroke Medicine

Background:

  • Recent myocardial infarction (MI) is a known risk factor for ischemic stroke.
  • Patients experiencing stroke during the peri-infarct period are often hospitalized, facilitating access to early cerebral reperfusion therapies.
  • However, recent MI is typically a contraindication for intravenous thrombolysis due to the risk of myocardial rupture.

Observation:

  • This case report details the successful use of intravenous thrombolysis in a patient who had an acute myocardial infarct within 48 hours.
  • The patient presented with acute ischemic stroke.

Findings:

  • Intravenous thrombolysis was administered safely and effectively in a patient with acute ischemic stroke and recent myocardial infarction.
  • This challenges the established contraindication for thrombolysis in this patient subgroup.

Implications:

  • The findings suggest that intravenous thrombolysis may be a viable treatment option for acute ischemic stroke in select patients with recent MI.
  • There is a need for evidence-based guidelines to manage stroke in patients with recent myocardial infarction.
  • Further research is warranted to establish the safety and efficacy of thrombolysis in this high-risk population.

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