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Updated: May 27, 2026

Realistic Membrane Modeling Using Complex Lipid Mixtures in Simulation Studies
Published on: September 1, 2023
[A kinetic lattice model of the chain-melting phase transition in lipid membrane: its experimental calibration and
Abstract:
A kinetic lattice model of chain-melting phase transition has been developed. Its time scale has been calibrated with the acoustic relaxation spectroscopic data. The model presents a tool for the analysis and predictions of kinetic features of those physiological processes in biological membranes whose mechanism is based on the phase transition in the lipid component. It has been shown that the phase-transitional mechanism can provide a high rate of synaptic exocytosis known for the fastest synapses in the central nervous system. It was also demonstrated that this mechanism can serve as an essential factor of synaptic plasticity.
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