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Updated: May 27, 2026

Analysis of Volatile and Oxidation Sensitive Compounds Using a Cold Inlet System and Electron Impact Mass Spectrometry
Published on: September 5, 2014
[ERIAD mass spectrometry (electrospray with controlled fragmentation) is the common method for metallomics and
Abstract:
The physical aspects of the ERIAD method (electrospray with controlled fragmentation) in terms of the problems of metallomics and biochemistry of elementoorganic compounds have been considered. It was shown that the method is well suited to study the objects of this class since it enables one to change from the molecular to the elemental analysis merely by changing the voltage between the nozzle and the skimmer. In the regime of molecular analysis, it is possible to determine the mass of the molecule as a whole and decipher its structure by controlled fragmentation, and in the regime of elemental analysis the number of atoms of heteroelements incorporated in the molecule can be quantified.
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