Cardiac biomarkers in neonatal hypoxic ischaemia
D Sweetman1, K Armstrong, J F A Murphy
1Neonatology, National Maternity Hospital, Dublin, Ireland. dsweetman@nmh.ie
Unlabelled:
Following a perinatal hypoxic-ischaemic insult, term infants commonly develop cardiovascular dysfunction. Troponin-T, troponin-I and brain natriuretic peptide are sensitive indicators of myocardial compromise. The long-term effects of cardiovascular dysfunction on neurodevelopmental outcome following perinatal hypoxic ischaemia remain controversial. Follow-up studies are warranted to ensure optimal cardiac function in adulthood.
Conclusion:
Cardiac biomarkers may improve the diagnosis of myocardial injury, help guide management, estimate mortality risk and may also aid in longterm neurodevelopmental outcome prediction following neonatal hypoxic-ischaemia.
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