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Isolation of Human Islets from Partially Pancreatectomized Patients
Published on: July 30, 2011
Coagulation abnormalities in deceased donors are associated with unsuccessful human islet cell isolation
Jong Man Kim1, Sang Man Jin, Seung Hoon Oh
1Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Republic of Korea.
Diabetes Research and Clinical Practice
|November 29, 2011
Abstract:
An equivalent islet number (EIN) greater than 300,000 is necessary for islet cell transplantation for a recipient who weighs about 60 kg. The aim of this study is to identify factors that affect isolation outcome. The most significant independent predictor for successful islet isolation from deceased donors was low international normalized ratio (INR).
