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In Vivo Confocal Microscopy in the Diagnosis and Management of Dry Eye: A Focus on Imaging Protocols and Interpretation

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Multiple evanescent white dot syndromes.

Ruwan A Silva¹, Thomas A Albini, Harry W Flynn

¹Department of Ophthalmology, Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, 900 NW 17th Street, Miami, FL, 33136, USA.

Journal of Ophthalmic Inflammation and Infection

|November 29, 2011

Summary

This summary is machine-generated.

This case study highlights multi-focal evanescent white dot syndrome (MEWDS), emphasizing foveal granularity as a key diagnostic sign. Spectral-domain optical coherence tomography (SD-OCT) confirms outer retina involvement in this condition.

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Multifocal Electroretinograms

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Published on: December 4, 2011

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Multifocal Electroretinograms

Multifocal Electroretinograms

Published on: December 4, 2011

Area of Science:

Ophthalmology
Retinal Imaging
Medical Case Reports

Background:

Multifocal evanescent white dot syndrome (MEWDS) is an inflammatory condition affecting the outer retina.
Its characteristic clinical presentation can sometimes be subtle, posing diagnostic challenges.

Purpose of the Study:

To report a case of MEWDS with classic foveal granularity.
To demonstrate outer retinal pathology using advanced imaging techniques.

Main Methods:

A case study methodology was employed.
Diagnostic tools included fundus autofluorescence, fluorescein angiography, indocyanine green angiography, and spectral-domain optical coherence tomography (SD-OCT).

Main Results:

A 34-year-old female presented with photopsias and blurred vision.
Foveal granularity was a prominent finding, consistent with MEWDS.
SD-OCT revealed increased retinal pigment epithelium granularity and disruption of the photoreceptor inner segment-outer segment junction subfoveally.

Conclusions:

Foveal granularity may be the most specific clinical feature of MEWDS.
SD-OCT is effective in localizing pathology to the outer retina in MEWDS, supporting a historically debated aspect of the condition.