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Related Concept Videos

Epigenetic Regulation01:37

Epigenetic Regulation

Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...
Epigenetic Regulation01:46

Epigenetic Regulation

Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
Epigenetic Regulation01:46

Epigenetic Regulation

Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.

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Updated: May 27, 2026

Reusable Single Cell for Iterative Epigenomic Analyses
10:28

Reusable Single Cell for Iterative Epigenomic Analyses

Published on: February 11, 2022

The USC Epigenome Center.

Peter W Laird1

  • 1University of Southern California, Keck School of Medicine, USC Epigenome Center, 1450 Biggy Street, Los Angeles, CA 90089-99601, USA. plaird@usc.edu

Epigenomics
|November 30, 2011
PubMed
Summary
This summary is machine-generated.

The University of Southern California established the USC Epigenome Center, a leading facility for high-throughput epigenomic data production and analysis. This center supports large-scale genomic studies and advances epigenetics research and training.

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Area of Science:

  • Genomics
  • Epigenetics
  • Bioinformatics
  • Translational Medicine

Background:

  • The University of Southern California (USC) has a strong history in epigenetics research.
  • Rapid advancements in epigenetics necessitate specialized infrastructure for high-throughput data generation.
  • A dedicated facility is crucial for USC to maintain its leadership in epigenomic studies.

Purpose of the Study:

  • To establish a large-scale academic center for epigenomic research at USC.
  • To provide high-throughput data production capabilities for extensive genomic and epigenomic studies.
  • To develop innovative analytical tools tailored for epigenomic research.

Main Methods:

  • Establishment of the USC Epigenome Center.
  • Implementation of high-throughput data production pipelines.
  • Development of novel bioinformatics tools for epigenomic data analysis.

Main Results:

  • The USC Epigenome Center is operational as the first academic facility of its kind.
  • The center is actively producing high-throughput data for large-scale projects.
  • New analysis tools for epigenomic research are under development.

Conclusions:

  • The USC Epigenome Center is a significant resource for advancing epigenetics research.
  • The facility will foster multidisciplinary collaboration in genomics, epigenomics, and bioinformatics.
  • It will also serve as a vital hub for education and training in these fields.