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Quantification, Viability Assessment, and Visualization Strategies for Acinetobacter Biofilms
Published on: August 4, 2023
[Acinetobacter baumannii - related mortality in intensive care units in Colombia]
Elkin V Lemos1, Fernando De la Hoz Restrepo, Nelson Alvis
1Universidad Nacional de Colombia, Bogotá, Colombia. elkin799@yahoo.com
Objective:
Compare mortality in multidrug-susceptible Acinetobacter baumannii infected patients and multidrug-resistant A. baumannii-infected patients hospitalized in intensive care units (ICUs) in Colombia.
Methods:
A prospective, observational, and multicenter study. A total of 165 patients admitted to the participating ICUs from April 2006 to April 2010 were included. On day 14 and day 30 of hospitalization, mortality in multidrug-resistant patients with clinical isolates of A. baumannii was compared with that in multidrug-susceptible patients.
Results:
Of the 165 adult patients who had health care-associated infections (HAI) caused by A. baumannii, multidrug-susceptible bacteria were found in 62 patients and multidrug-resistant bacteria in 103. Statistically significant differences in mortality on day 14 of hospitalization in the ICU were not found. On the other hand, significant differences (P < 0.05) in mortality on day 30 of hospitalization were observed between patients with multidrug-resistant isolates and those with multidrug-susceptible isolates. This difference was maintained when the patients' risk factors were evaluated by multivariate analysis.
Conclusions:
The presence of multidrug resistance is the primary risk factor for mortality in patients with HAI caused by A. baumannii in Colombian ICUs.
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