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Published on: June 18, 2020
A manganese-ferritin nanocomposite as an ultrasensitive T2 contrast agent
Barindra Sana1, Chueh Loo Poh, Sierin Lim
1Division of Bioengineering, School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore 637457.
Chemical Communications (Cambridge, England)
|November 30, 2011
Abstract:
T(2) contrast is gaining importance in high field strength MRI. We report a strategy for developing a T(2) contrast agent from paramagnetic metal ions synthesized within an engineered protein cage. The manganese-ferritin nanocomposite showed high T(2) relaxivity indicating its potential as an ultrasensitive T(2) contrast agent.
