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Procedure for creating a three-dimensional (3D) model for superficial hyperthermia treatment planning.

Marianne Linthorst1, Tomas Drizdal, Hans Joosten

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Summary

Creating patient-specific 3D models from CT scans enables precise superficial hyperthermia treatment planning (SHTP). This method refines radiotherapy (RT) and hyperthermia (HT) for breast cancer patients, improving treatment accuracy.

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Area of Science:

  • Medical Imaging
  • Radiation Oncology
  • Computational Modeling

Background:

  • Superficial hyperthermia treatment planning (SHTP) requires patient-specific models.
  • Accurate 3D models are crucial for optimizing radiotherapy (RT) and hyperthermia (HT) delivery.

Purpose of the Study:

  • To develop a method for creating patient- and treatment-specific computed tomography (CT) scans.
  • To generate a three-dimensional (3D) patient model for SHTP.

Main Methods:

  • Included patients with recurrent breast adenocarcinoma undergoing RT and HT.
  • Performed CT scans after thermometry catheter insertion.
  • Implemented procedural adjustments including radioopaque markers and modified CT timing.
  • Segmented CT slices and manually outlined structures using iSeg software.
  • Imported models into SEMCAD X for 3D electromagnetic simulation.

Main Results:

  • A total of 26 patients were included.
  • Five procedural adjustments were made to optimize CT scan information.
  • Successful segmentation of CT slices into tissue types.
  • Manual outlining of RT fields, catheters, and tumor lesions.
  • Generation of 3D models for electromagnetic simulation.

Conclusions:

  • The finalized procedure enables the creation of patient- and treatment-specific CT scans.
  • This facilitates the generation of accurate 3D models essential for SHTP.