Related Experiment Video
Updated: May 27, 2026

Cervical Lymph Duct-Cannulated Rat Model for Assessing Lymphatic Transport from the Head and Brain
Published on: March 10, 2026
[Primary cranial vault lymphoma]
Daniel Castro-Bouzas1, Ángel Prieto-González, Ramón Serramito-García
1Servicio de Neurocirugía, Departamento de Cirugía, Universidad de Santiago de Compostela, Hospital Clínico Universitario de Santiago, Santiago de Compostela, A Coruña, España. danicastrobouzas@yahoo.es
Introduction:
Primary bone lymphomas account for 3-7% of all malignant bone tumours and less than 2% of lymphomas in adults. Having the cranial vault as their primary location is very infrequent.
Case Report:
A 59-year-old female who presented a painful tumour on the cranial vault which, following radical surgical removal, was found to be an ALK-negative primary large-cell lymphoma.
Conclusions:
After reviewing the literature we believe that this is the first case of cranial vault lymphoma in which the translocation of the ALK protein-producing gene has been studied.
Related Concept Videos
Primary Lymphoid Organs
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
Secondary Lymphoid Organs
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
Cranial and Spinal Meninges
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...
Lymphoid Cells and Tissues
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
Increased Intracranial Pressure l: Introduction
Graves' Disease I: Introduction
