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Analysis of skeletal muscle hypertrophy in models of increased loading

Sue C Bodine1, Keith Baar

  • 1Department of Neurobiology, University of California, Davis, CA, USA. scbodine@ucdavis.edu

Methods in Molecular Biology (Clifton, N.J.)
|December 2, 2011
PubMed

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Hypertrophy is the increase in the size of individual cells, resulting in the enlargement of a tissue or organ. Unlike hyperplasia, which involves an increase in cell number, hypertrophy is characterized by an increase in cell volume. This process often occurs in response to higher functional demand or hormonal stimulation, leading to the production of more structural proteins and organelles, thereby enhancing the cells' work capacity.There are two primary types of hypertrophy: physiological...