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Updated: May 27, 2026

Transauricular Vagus Nerve Stimulation and Electroencephalographic Assessment in Disorders of Consciousness
Published on: July 11, 2025
Microswitch technology and contingent stimulation to promote adaptive engagement in persons with minimally conscious
Giulio E Lancioni1, Nirbhay N Singh, Mark F O'Reilly
1Department of Psychology, University of Bari, Via Quintino Sella 268, 70100, Bari, Italy. g.lancioni@psico.uniba.it
Abstract:
This study assessed whether a post-coma woman functioning at the lower end of the minimally conscious state would (a) develop adaptive responding through the use of microswitch technology and contingent stimulation, (b) consolidate and maintain her responding over time, and (c) show evidence of response-consequences awareness (learning and discrimination). The study involved an ABABB1CB1 sequence in which the A represented baseline phases, the B and B1 intervention phases, and the C a control phase with continuous stimulation. Results indicated that the woman developed adaptive responding and consolidated it over the intervention phases of the study. The woman also showed evidence of being aware of response-consequences links. Potential implications and limitations of these findings are discussed.
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