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Related Concept Videos

Visual Agnosia01:12

Visual Agnosia

Visual agnosia is a condition characterized by the inability to recognize visually presented objects despite having normal vision. For instance, a person with visual agnosia can describe the shape and color of an object but cannot identify or name it. This impairment does not affect their visual field, acuity, color vision, brightness discrimination, language, or memory. An example of this condition in a social setting is someone at a dinner party asking for "that silver thing with a round end"...
Association Areas of the Cortex01:21

Association Areas of the Cortex

Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...

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Computerized visual field defects in posterior cortical atrophy.

Victoria S Pelak1, Shawn F Smyth, Philip J Boyer

  • 1Department of Neurology, University of Colorado Denver School of Medicine, Denver, CO, USA. victoria.pelak@ucdenver.edu

Neurology
|December 2, 2011
PubMed
Summary
This summary is machine-generated.

Computerized visual field (CVF) defects in posterior cortical atrophy (PCA) often present as homonymous visual field loss or constriction. These findings may indicate PCA, prompting early evaluation, especially in patients with driving difficulties.

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Area of Science:

  • Neuroscience
  • Ophthalmology
  • Neurology

Background:

  • Posterior cortical atrophy (PCA) is a neurodegenerative syndrome characterized by visual dysfunction.
  • Visual field defects in PCA have not been systematically described using computerized visual field (CVF) perimetry.
  • Understanding these defects is crucial for diagnosing PCA and differentiating it from other neurodegenerative conditions.

Purpose of the Study:

  • To systematically describe visual field defects in patients with posterior cortical atrophy (PCA) using computerized visual field (CVF) perimetry.
  • To analyze the characteristics of CVF defects in PCA.
  • To correlate CVF findings with clinical presentation and underlying pathology.

Main Methods:

  • Retrospective case series of patients meeting PCA diagnostic criteria.
  • Analysis of clinical history, neurological examination, neuroimaging, and CVF data.
  • Patients evaluated between 2002 and 2006 at specialized neuro-ophthalmology and neurobehavior clinics.

Main Results:

  • Nine patients with PCA underwent CVF testing.
  • Seven patients exhibited homonymous hemianopia or quadrantanopia; two had bilateral constriction.
  • All patients progressed to dementia, with most meeting criteria for Alzheimer disease (AD) or dementia with Lewy bodies.
  • Driving difficulties were reported early by seven patients.

Conclusions:

  • CVF defects in PCA include homonymous visual field defects and bilateral constriction.
  • These CVF patterns differ from those typically seen in Alzheimer disease.
  • CVF testing is recommended for older adults with unexplained visual complaints and driving difficulties, as it may suggest PCA and facilitate early evaluation.