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Updated: May 27, 2026

09:22
Direct Synthesis of EM-Visible Gold Nanoparticles in Cells for Protein Localization Analysis with Well-Preserved Ultrastructure
Published on: April 28, 2023
Bifunctional peptides that precisely biomineralize Au clusters and specifically stain cell nuclei
Yaling Wang1, Yanyan Cui, Yuliang Zhao
1Institute of High Energy Physics, Chinese Academy of Sciences, Yuquan Road 19B, Shi Jing Shan District, Beijing 10049, China.
Abstract:
A bifunctional peptide containing a domain that targets cell nuclei and a domain with the ability to biomineralize and capture Au clusters is presented. The peptide-Au clusters exhibit red emission (λ(em) = 677 nm) and specifically stain the nuclei of three cell lines.

