Related Experiment Video
Updated: May 27, 2026
08:13
In Vivo Confocal Microscopy in the Diagnosis and Management of Dry Eye: A Focus on Imaging Protocols and Interpretation
Published on: November 11, 2025
[Follicular conjunctivitis of unknown origin]
S Goebels1, A K Hasenfus, B K Kellner
1Klinik für Augenheilkunde, Universitätsklinikum des Saarlandes UKS, Homburg, Deutschland. susanne.goebels@uks.eu
Summary
A chronic conjunctivitis case was initially misdiagnosed but later identified as follicular lymphoma, a B-cell non-Hodgkin lymphoma. Successful radiotherapy treatment led to symptom resolution.
Area of Science:
- Ophthalmology
- Oncology
- Pathology
Background:
- Chronic conjunctivitis can present diagnostic challenges.
- Giant papillary conjunctivitis is a common misdiagnosis for persistent ocular inflammation.
Observation:
- A 40-year-old female chemical laboratory assistant presented with a 4-year history of chronic conjunctivitis.
- Initial topical treatments for presumed giant papillary conjunctivitis were ineffective.
Findings:
- Histopathological analysis of a biopsy revealed bilateral follicular lymphoma.
- Follicular lymphoma is a type of B-cell non-Hodgkin lymphoma affecting the conjunctiva.
Implications:
- This case highlights the importance of considering rare diagnoses in persistent ocular conditions.
- Prompt diagnosis and radiotherapy can effectively manage conjunctival lymphoma, leading to symptom remission.
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