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Opsono-Adherence Assay to Evaluate Functional Antibodies in Vaccine Development Against Bacillus anthracis and Other Encapsulated Pathogens
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Glycoconjugates prevent B. anthracis toxin-induced cell death through binding while activating macrophages.

Olga Tarasenko1, Ashley Scott, Lee Soderberg

  • 1Department of Biology, University of Arkansas at Little Rock, 72204, USA. omtarasenko@ualr.edu

Glycoconjugate Journal
|December 3, 2011
PubMed
Summary

Glycoconjugate-bearing polymers protect macrophages from Bacillus anthracis toxins. These polymers activate macrophages, increasing nitric oxide production and enhancing cell viability against toxin-induced death.

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