Related Experiment Video
Updated: May 27, 2026
05:53
Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
Published on: June 21, 2018
A 48-plex autosomal SNP GenPlex™ assay for human individualization and relationship testing.
Carmen Tomas1, Claus Børsting, Niels Morling
1Section of Forensic Genetics, Department of Forensic Medicine, University of Copenhagen, Copenhagen, Denmark. carmen.tomas@forensic.ku.dk
Methods in Molecular Biology (Clifton, N.J.)
|December 6, 2011
Summary
The GenPlex™ HID system protocol offers a new platform for SNP typing in forensic science. This system, including 48 SNPforID SNPs and amelogenin, has been validated in multiple forensic laboratories.
Area of Science:
- Forensic Science
- Genetics
- Molecular Biology
Background:
- Single Nucleotide Polymorphisms (SNPs) are gaining prominence in forensic applications.
- Various SNP typing platforms exist, necessitating evaluation of new technologies.
Purpose of the Study:
- To describe the GenPlex™ HID system protocol, a novel SNP typing platform.
- To present the performance of this system in forensic laboratory settings.
Main Methods:
- The GenPlex™ HID system protocol utilizes 48 of the 52 SNPforID SNPs and amelogenin.
- The protocol was tested by multiple forensic laboratories.
Main Results:
- The GenPlex™ HID system protocol was successfully implemented in forensic laboratory testing.
- The system demonstrated effectiveness with both ordinary and forensic samples.
Conclusions:
- The GenPlex™ HID system protocol is a viable new platform for forensic SNP typing.
- Validation across different laboratories confirms its practical utility in forensic casework.
