Related Experiment Video
Updated: May 26, 2026

09:27
DNA Microarrays: Sample Quality Control, Array Hybridization and Scanning
Published on: March 15, 2011
Improving the homogeneity of DNA patterning on microarrays
1Department of Radiology, Cincinnati Children's Hospital, 3333 Burnet Ave., MLC 5033, Cincinnati, OH 45229, USA. patrick.winter@cchmc.org
Nanomedicine (London, England)
|December 6, 2011
Summary
No abstract available in PubMed .
Related Concept Videos
DNA Microarrays
Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...
Position-effect Variegation
In 1928, a German botanist Emil Heitz observed the moss nuclei with a DNA binding dye. He observed that while some chromatin regions decondense and spread out in the interphase nucleus, others do not. He termed them euchromatin and heterochromatin, respectively. He proposed that the heterochromatin regions reflect a functionally inactive state of the genome. It was later confirmed that heterochromatin is transcriptionally repressed, and euchromatin is transcriptionally active chromatin.

