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Teeth

Teeth

The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...

Overview of Regeneration and Repair

Overview of Regeneration and Repair

Regeneration and repair processes are critical in healing damages caused by injury, disease, and aging. In regeneration, the damaged tissue is entirely replaced with new growth that restores the original architecture and function. In contrast, tissue repair usually results in a fixed tissue architecture involving scar formation. Scars generally do not reestablish tissue function and may also exhibit structural abnormalities at the injury site.
Regeneration
All animals have varying degrees of...

Whole Body Regeneration

Whole Body Regeneration

Regeneration is the process of restoring injured or lost tissues, organs, or body parts. While simpler organisms generally show greater ability to regenerate their whole body, few complex animals show similarly exceptional regeneration. For example, planarian flatworms have a unique regenerative potential making them a popular study organism among biologists to understand the mechanisms of whole body regeneration. Other organisms, such as hydra, also show extreme regeneration potential; even...

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Related Experiment Video

Updated: May 26, 2026

Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease

Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease

Published on: May 9, 2022

Regenerative periodontal therapy.

Daniel W K Kao¹, Joseph P Fiorellini

¹Department of Periodontics, University of Pennsylvania, Philadelphia, PA, USA.

Frontiers of Oral Biology

|December 7, 2011

Summary

This summary is machine-generated.

Periodontal disease treatments are shifting from repair to regeneration. Proteins show promise in promoting bone regrowth, offering a new avenue for treating bone and attachment loss.

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Induction of Periodontitis via a Combination of Ligature and Lipopolysaccharide Injection in a Rat Model

Induction of Periodontitis via a Combination of Ligature and Lipopolysaccharide Injection in a Rat Model

Published on: February 17, 2023

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Last Updated: May 26, 2026

Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease

Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease

Published on: May 9, 2022

Induction of Periodontitis via a Combination of Ligature and Lipopolysaccharide Injection in a Rat Model

Induction of Periodontitis via a Combination of Ligature and Lipopolysaccharide Injection in a Rat Model

Published on: February 17, 2023

Area of Science:

Periodontal medicine
Regenerative dentistry
Biomaterials science

Background:

Periodontal disease causes significant bone and attachment loss.
Traditional treatments focus on repairing damage.
Regenerative techniques aim to rebuild lost structures.

Purpose of the Study:

To explore regenerative techniques for periodontal defects.
To investigate pharmacologically based approaches for bone regrowth.
To evaluate the role of proteins in periodontal wound healing and bone formation.

Main Methods:

Review of conventional regenerative procedures using barrier membranes and bone grafts.
Exploration of pharmacologically based strategies for osseous regeneration.
Analysis of clinical research on protein-mediated bone formation.

Main Results:

Conventional regenerative techniques have limitations in predictability.
Pharmacological approaches are being investigated to enhance osseous regrowth.
Proteins are identified as potent biological mediators in wound healing and bone formation.

Conclusions:

Regenerative medicine offers a promising alternative to traditional periodontal treatments.
Proteins hold significant potential for promoting bone regeneration in periodontal defects.
Further research into protein-based therapies could revolutionize periodontal treatment outcomes.