Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Spongy Bone01:09

Spongy Bone

All bones comprise an outer layer of compact bone, and an interior made up of spongy bone tissue, also called cancellous or trabecular bone. In long bones, spongy bone tissue is mainly found in the interior of the epiphyses (broad ends of the bone).
Spongy bone is more porous, and less dense compared to compact bone. It is composed of concentric lamellae that are arranged irregularly to form the trabecular network. In some bones, the spaces between trabeculae contain red marrow, where...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High-Statistics Measurement of the Cosmic-Ray Electron Spectrum with H.E.S.S.

Physical review letters·2024
Same author

The accelerated weight histogram method for alchemical free energy calculations.

The Journal of chemical physics·2021
Same author

Effects of sodium bicarbonate infusion on mortality in medical-surgical ICU patients with metabolic acidosis-A single-center propensity score matched analysis.

Medicina intensiva·2021
Same author

Habitual dietary fibre and prebiotic intake is inadequate in patients with inflammatory bowel disease: findings from a multicentre cross-sectional study.

Journal of human nutrition and dietetics : the official journal of the British Dietetic Association·2020
Same author

Albumin and calcium reference interval using healthy individuals and a data-mining approach.

Annals of clinical biochemistry·2020
Same author

In search of a one plan solution for VMAT post-mastectomy chest wall irradiation.

Journal of applied clinical medical physics·2020
Same journal

Effects of CFR-PEEK plate layup and screw configuration on tibial shaft fracture healing: a simulation study based on a mechanobiological model.

Computer methods in biomechanics and biomedical engineering·2026
Same journal

Metabolic rate-limiting enzyme-associated genes as novel biomarkers for prognosis and treatment response in lung adenocarcinoma.

Computer methods in biomechanics and biomedical engineering·2026
Same journal

An interpretable, clinically-aligned AI paradigm for VTE risk prediction: an approach using LLMs and compound attention.

Computer methods in biomechanics and biomedical engineering·2026
Same journal

Effects of different resistance loads during resisted sprint running on internal stresses of the ankle joint: a finite element analysis.

Computer methods in biomechanics and biomedical engineering·2026
Same journal

Analysis of typical cases of medical infusion pump metering acceptance in nursing scenarios.

Computer methods in biomechanics and biomedical engineering·2026
Same journal

Investigation of biomechanical effect of inverted orthotic insoles on flexible flatfeet.

Computer methods in biomechanics and biomedical engineering·2026
See all related articles

Related Experiment Video

Updated: May 26, 2026

A Minimally Invasive Model to Analyze Endochondral Fracture Healing in Mice Under Standardized Biomechanical Conditions
06:41

A Minimally Invasive Model to Analyze Endochondral Fracture Healing in Mice Under Standardized Biomechanical Conditions

Published on: March 22, 2018

An approximate model for cancellous bone screw fixation.

C J Brown1, R A Sinclair, A Day

  • 1School of Engineering and Design, Brunel University, Uxbridge, UB8 3PH, UK. chris.brown@brunel.ac.uk

Computer Methods in Biomechanics and Biomedical Engineering
|December 14, 2011
PubMed
Summary
This summary is machine-generated.

Finite element models show calcium phosphate cement significantly improves screw fixation in weak cancellous bone. This enhanced bone screw fixation can lead to better fracture healing and treatment outcomes.

More Related Videos

An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice
07:41

An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice

Published on: November 13, 2016

Adjustable Stiffness, External Fixator for the Rat Femur Osteotomy and Segmental Bone Defect Models
10:09

Adjustable Stiffness, External Fixator for the Rat Femur Osteotomy and Segmental Bone Defect Models

Published on: October 9, 2014

Related Experiment Videos

Last Updated: May 26, 2026

A Minimally Invasive Model to Analyze Endochondral Fracture Healing in Mice Under Standardized Biomechanical Conditions
06:41

A Minimally Invasive Model to Analyze Endochondral Fracture Healing in Mice Under Standardized Biomechanical Conditions

Published on: March 22, 2018

An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice
07:41

An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice

Published on: November 13, 2016

Adjustable Stiffness, External Fixator for the Rat Femur Osteotomy and Segmental Bone Defect Models
10:09

Adjustable Stiffness, External Fixator for the Rat Femur Osteotomy and Segmental Bone Defect Models

Published on: October 9, 2014

Area of Science:

  • Biomedical Engineering
  • Orthopedic Surgery
  • Materials Science

Background:

  • Achieving stable screw fixation in low-density cancellous bone is challenging for effective fracture treatment.
  • Inadequate screw holding power can compromise bone healing and treatment success.
  • Current fixation techniques may not provide sufficient stability in compromised bone quality.

Purpose of the Study:

  • To develop and utilize a finite element (FE) model to identify key parameters influencing cancellous bone screw fixation.
  • To evaluate the potential of bone cements to enhance screw holding power and improve fracture fixation.
  • To compare the effectiveness of different screw, bone, and cement configurations for optimal orthopedic applications.

Main Methods:

  • Development of a predictive finite element (FE) model simulating screw fixation in cancellous bone.
  • Analysis of parameters affecting screw pull-out strength under various experimental setups.
  • Comparative evaluation of different screw designs and cement augmentation strategies.

Main Results:

  • FE models demonstrated that bone cements can substantially improve screw holding power in cancellous bone.
  • Identified key parameters critical for maximizing screw pull-out strength.
  • Showcased significant improvements in screw fixation strength with cement augmentation.

Conclusions:

  • Appropriate use of calcium phosphate cement can increase screw pull-out strength in cancellous bone by up to an order of magnitude.
  • Cement augmentation offers a promising strategy to enhance screw fixation for improved fracture treatment.
  • This FE modeling approach provides valuable insights for optimizing orthopedic fixation devices.