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Breathing-controlled Electrical Stimulation (BreEStim) for Management of Neuropathic Pain and Spasticity

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An integrated implantable electrical sacral root stimulator for bladder control.

A Uranga¹, N Barniol, D Marín

¹Departament d'Enginyeria Electrònica. Universitat Autònoma de Barcelona, and Centro Nacional de Microelectrónica (CNM-IMB) Campus UAB, Bellaterra, Spain.

Neuromodulation : Journal of the International Neuromodulation Society

|December 14, 2011

Summary

This summary is machine-generated.

This study developed an implantable electrical system for sacral root stimulation to restore micturition, defecation, and erection functions in paraplegic patients. The system offers programmable, distance-independent control for enhanced functional recovery.

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Area of Science:

Biomedical Engineering
Neuroprosthetics
Implantable Medical Devices

Background:

Paraplegic patients experience loss of basic bodily functions due to spinal cord injury.
Restoring micturition, defecation, and erection is crucial for quality of life.

Purpose of the Study:

To develop and study an integrated electrical system for sacral root stimulation.
To enable control of micturition, defecation, and erection in paraplegic individuals.

Main Methods:

Utilized Mietec CMOS technology for system implementation.
Designed an external transceiver and an implantable batteryless module.
Incorporated a bi-directional inductive link for data and energy transfer.
Included an impedance measurement circuit for performance testing.

Main Results:

Achieved independent control of stimulation parameters (amplitude, pulse width, frequency).
Demonstrated waveform control independent of external coil placement.
Validated the system's ability to control bladder voiding through sacral root stimulation.

Conclusions:

The developed stimulator architecture is effective for sacral root application.
The system provides independent, distance-programmable stimulation.
The integrated impedance measurement facilitates systematic performance testing.