Related Experiment Video
Updated: May 26, 2026

16:15
Mouse Kidney Transplantation: Models of Allograft Rejection
Published on: October 11, 2014
Ureteral replacement with appendix in pediatric renal transplantation
Juan P Corbetta1, Santiago Weller, Juan I Bortagaray
1Department of Urology, Hospital de Pediatría Prof. Dr. Juan P. Garrahan, Buenos Aires, Argentina. juancorbetta@gmail.com
Pediatric Transplantation
|December 14, 2011
Summary
Ureteral necrosis, a rare complication of radiation therapy (RT), may necessitate ureteral substitution. This study explores using the appendix for left ureteral replacement in children, assessing graft function.
Area of Science:
- Urology
- Pediatric Surgery
- Radiation Oncology
Background:
- Ureteral necrosis is an infrequent yet significant complication after radiation therapy (RT), potentially compromising patient outcomes.
- Preservation of the native ureter is generally preferred, but ureteral substitution becomes necessary when graft function is at risk.
- Limited literature exists regarding appendiceal use for left ureteral replacement in pediatric cases.
Observation:
- This report details two pediatric cases where the appendix was utilized for left ureteral substitution.
- The study focuses on evaluating the functional evolution of the appendiceal graft in these patients.
Findings:
- The appendix served as a viable conduit for left ureteral replacement in the presented pediatric cases.
- Assessment of graft function over time is crucial for understanding long-term outcomes.
Implications:
- Appendiceal ureteral substitution presents a potential solution for managing ureteral necrosis in children post-RT.
- Further research is warranted to establish the efficacy and long-term safety of this technique in pediatric urology.
Related Concept Videos
Kidney Transplant II: Surgical Procedure
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Kidney Transplant I: Introduction
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Kidney Transplant III: Nursing Management
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
Anatomy of the Genitourinary System I: Kidneys and Ureters
The upper urinary system comprises two kidneys and two ureters, which are crucial in filtering blood and forming urine.KidneysLocation and Structure:The kidneys are two bean-shaped organs positioned behind the peritoneum on either side of the spine.Kidneys are between the 12th thoracic (T12) and the 3rd lumbar (L3) vertebrae.The position of the liver causes the right kidney to sit slightly lower than the left.Protective Layers:Each kidney is enveloped in a tough, fibrous membrane called the...
