[Antibody-dependent cell-mediated immune reactions in experimental trichinelliasis in mice]

The experiments on mice experimentally infected with Trichinella larvae have established that in mild infection adhesive and killer cell reactions developed on day 14, reached their maximum on days 21-30 and began to attenuate on day 45. The cells from animals with moderate infection showed a higher immune activity which remained unchanged till day 90 of infection. The cells from mice with severe infection showed inhibition of immune activity which was most marked on days 21 and 30 of the infection. Eosinophiles and neutrophils are characterized by IgE-dependent cell adherence and killing activity, the involvement of macrophages in the responses seems to be insignificant.