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Published on: September 5, 2011
Unilateral primary pulmonary agenesis and hypoplasia in monozygotic twins
Muslim Alsaadi1, Badr Al Muqhem, A Boukai
1Department of Pediatrics, Division of Respiratory Medicine; Department of Radiology, College of Medicine, King Saud University, Riyadh, Saudi Arabia. alsaadi@ksu.edu.sa
Abstract:
We describe 10-month-old identical female twin infants, one with primary left-sided pulmonary agenesis and the other with primary left-sided pulmonary hypoplasia. They came to our outpatient clinic complaining of persistent dry cough. The clinical examination revealed decreased air entry over the left hemithorax. Chest x-rays showed complete left-sided radio-opacity in both the twins. The chest computed tomography scan with contrast confirmed the diagnoses of left-sided pulmonary agenesis (twin A) and left-sided hypoplasia (twin B). No other associated congenital anomaly was noted in either of the twins. To our knowledge, such a condition in live monozygotic twins has not been previously reported in published studies.
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