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Hemolytic uremic syndrome induced by infusion of oxaliplatin: a case report
Patrizia Racca1, Rosella Spadi, Gianluca Fora
1SSCVD Colorectal Cancer Unit, and 2SC Medical Oncology 1, AOU San Giovanni Battista, Turin, Italy. pracca@molinette.piemonte.it
Introduction:
Oxaliplatin is a third-generation platinum compound with proven antitumor activity in the treatment of colorectal cancer. The occurrence of life-threating hemolitic uremic syndrome has been observed after oxaliplatin therapy. The kind of tumor and treatment modalities seem to influence the onset of hemolitic uremic syndrome.
Methods:
The clinical course of the case is reviewed and compared with reports of other similar cases in the literature.
Results:
We describe the development of hemolitic uremic syndrome as a result of prolonged oxaliplatin treatment of a colon cancer patient.
Conclusions:
Although this rare event requires the concurrence of other unknown factors, it should be considered in a decision-making setting.
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