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Preparation, Administration, and Assessment of In Vivo Tissue-Specific Cellular Uptake of Fluorescent Dye-Labeled Liposomes
Published on: July 30, 2020
Cellular uptake of a fluorescent vanadyl sulfonylcalix[4]arene
Carl Redshaw1, Mark R J Elsegood, Joseph A Wright
1Energy Materials Laboratory, School of Chemistry, The University of East Anglia, Norwich, NR4 7TJ, UK.
Chemical Communications (Cambridge, England)
|December 14, 2011
Abstract:
Vanadyl bearing calix[4]arene ligands have undergone evaluation against several cell lines, and show varying degrees of toxicity. For vanadyl complexed to a sulfonylcalix[4]arene, monitoring of the strong blue fluorescence revealed slow uptake kinetics. The complex is exclusively found in the cytoplasm of the cells and uptake is not due to active endocytotic mechanisms.
