Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 26, 2026

Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes
04:08

Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes

Published on: June 27, 2025

First trimester miscarriage evaluation.

Ruth B Lathi1, Florette K Gray Hazard, Amy Heerema-McKenney

  • 1Department of Obstetrics and Gynecology, Recurrent Pregnancy Loss Program, Stanford University, Stanford, California 94305, USA. rlathi@stanford.edu

Seminars in Reproductive Medicine
|December 14, 2011
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development of Small-Molecule Allosteric Modulators of Beta-Galactosidase (β-Gal) for the Treatment of GM1 Gangliosidosis and Morquio B.

International journal of molecular sciences·2026
Same author

The Human Intolerome: A curated database to prioritize genomic variants in stillbirth, pregnancy loss, and neonatal death.

Genetics in medicine : official journal of the American College of Medical Genetics·2026
Same author

Leveraging health records to identify diagnoses associated with recurrent pregnancy loss across two medical centers.

iScience·2026
Same author

Maternal and fetal outcomes after recurrent pregnancy loss in an exclusively black cohort.

Journal of the National Medical Association·2026
Same author

Modeling human embryo implantation in vitro.

Cell·2025
Same author

Mapping Chemical-Gene Interactions for Developmental Lethality and Pregnancy Loss.

medRxiv : the preprint server for health sciences·2025

Chromosomal analysis of miscarriage tissue can explain over 50% of pregnancy losses. Early genetic testing and a multidisciplinary approach are crucial for understanding causes and recurrence risks.

Area of Science:

  • Reproductive Medicine
  • Genetics
  • Obstetrics

Background:

  • Miscarriage is common in healthy women, yet its causes are infrequently investigated.
  • Sporadic chromosome errors are the most frequent cause of miscarriage.

Purpose of the Study:

  • To highlight the importance of evaluating miscarriage causes.
  • To emphasize the role of genetic testing and a multidisciplinary approach.

Main Methods:

  • Chromosomal analysis of miscarriage tissue.
  • Ultrasound for gestational age and embryonic abnormalities.
  • Pathological examination for rare disorders.

Main Results:

  • Chromosomal analysis provides an explanation in at least 50% of cases.

Related Experiment Videos

Last Updated: May 26, 2026

Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes
04:08

Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes

Published on: June 27, 2025

  • Conventional cytogenetic evaluation requires fresh tissue, necessitating timely physician consideration.
  • Pathology can rule out rare, high-recurrence-risk disorders.

    • Conclusions:

    • A multidisciplinary evaluation is essential for understanding miscarriage etiology and recurrence risk.
    • Comprehensive evaluation and emotional support aid patient confidence for future pregnancies.