Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Microbial Biosensors01:17

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

'Raise the Bar', a Canadian intervention to combat disparities in the recognition and management of iron deficiency: Development of the intervention, feasibility and implementation.

British journal of haematology·2025
Same author

Efficient Dual Surface Modification of Cellulose Nanocrystals with Hydrophobic Moieties and Functional Polymers via a Grafting-to Approach.

Biomacromolecules·2025
Same author

The Binding Affinities of Serum Proteins to Nanoparticles.

Journal of the American Chemical Society·2025
Same author

Cellular Uptake of Upconversion Nanoparticles Based on Surface Polymer Coatings and Protein Corona.

ACS applied materials & interfaces·2024
Same author

Improved efficacy of FKRP AAV gene therapy by combination with ribitol treatment for LGMD2I.

Molecular therapy : the journal of the American Society of Gene Therapy·2023
Same author

Correction: Virtual microwells for digital microfluidic reagent dispensing and cell culture.

Lab on a chip·2023
Same journal

RETRACTED: Zhang et al. A Novel Framework for Reconstruction and Imaging of Target Scattering Centers via Wide-Angle Incidence in Radar Networks. <i>Sensors</i> 2025, <i>25</i>, 6802.

Sensors (Basel, Switzerland)·2026
Same journal

Enhancing Unsupervised Multi-Source Domain Adaptation for Person Re-Identification via Mixture of Experts and Graph-Based Relation.

Sensors (Basel, Switzerland)·2026
Same journal

Development of an Instrumented Glove for Palmar Pressure Assessment in Kayakers.

Sensors (Basel, Switzerland)·2026
Same journal

Development and Experimental Validation of an Autonomous IoT-Based Monitoring System for Real-Time Water Quality Assessment in the Amazon River.

Sensors (Basel, Switzerland)·2026
Same journal

Semi-Supervised Adversarial Learning Framework for Controller Area Network Bus Intrusion Detection.

Sensors (Basel, Switzerland)·2026
Same journal

Smart Optimization Method for Safety Signs in Innovative Manufacturing Environments Integrating Industrial Field IoT Sensors and Knowledge Graphs.

Sensors (Basel, Switzerland)·2026
See all related articles

Related Experiment Video

Updated: May 26, 2026

Fluorescent Lateral Flow Immunoassay Based on Quantum Dots Nanobeads
07:13

Fluorescent Lateral Flow Immunoassay Based on Quantum Dots Nanobeads

Published on: June 28, 2024

Biosensing with quantum dots: a microfluidic approach.

Charles H Vannoy1, Anthony J Tavares, M Omair Noor

  • 1Chemical Sensors Group, Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Rd. North, Mississauga, Ontario L5L 1C6, Canada. vannoy@utoronto.ca

Sensors (Basel, Switzerland)
|December 14, 2011
PubMed
Summary
This summary is machine-generated.

Semiconductor quantum dots (QDs) integrated into microfluidic systems (MFS) offer enhanced biosensing capabilities. This combination accelerates reaction rates and improves detection sensitivity for innovative bioassay designs.

Keywords:
biomarkersbiosensordiagnosticsfluorescence resonance energy transferimmobilizationmicrofluidicsmultiplexingnucleic acidsquantum dots

More Related Videos

Synthesis and Operation of Fluorescent-core Microcavities for Refractometric Sensing
08:12

Synthesis and Operation of Fluorescent-core Microcavities for Refractometric Sensing

Published on: March 13, 2013

Fluorescence detection methods for microfluidic droplet platforms
14:16

Fluorescence detection methods for microfluidic droplet platforms

Published on: December 10, 2011

Related Experiment Videos

Last Updated: May 26, 2026

Fluorescent Lateral Flow Immunoassay Based on Quantum Dots Nanobeads
07:13

Fluorescent Lateral Flow Immunoassay Based on Quantum Dots Nanobeads

Published on: June 28, 2024

Synthesis and Operation of Fluorescent-core Microcavities for Refractometric Sensing
08:12

Synthesis and Operation of Fluorescent-core Microcavities for Refractometric Sensing

Published on: March 13, 2013

Fluorescence detection methods for microfluidic droplet platforms
14:16

Fluorescence detection methods for microfluidic droplet platforms

Published on: December 10, 2011

Area of Science:

  • Nanotechnology
  • Biomedical Engineering
  • Analytical Chemistry

Background:

  • Semiconductor quantum dots (QDs) possess unique optical properties, making them suitable for fluorescence resonance energy transfer (FRET) and optical multiplexing in biosensing.
  • Current QD-based biosensors often operate in bulk solutions, leading to slow signal stabilization due to diffusion-controlled binding events.
  • Microfluidic systems (MFS) offer an alternative architecture for biosensor design, integrating biological and chemical processes on a single platform.

Purpose of the Study:

  • To review the key concepts and applications of quantum dot (QD)-based microfluidic biosensors.
  • To emphasize how the integration of QDs and MFS drives innovation in bioassay design.
  • To highlight the advantages of QD-based microfluidic biosensors over traditional methods.

Main Methods:

  • Review of existing literature on QD-based microfluidic biosensors.
  • Analysis of QD optical properties and their application in FRET and multiplexing.
  • Discussion of microfluidic system principles for enhanced reaction kinetics and sample manipulation.

Main Results:

  • QD-based microfluidic biosensors leverage unique optical properties for sensitive detection.
  • Microfluidic systems enable manipulation of flow conditions, overcoming diffusion limitations for faster signal generation.
  • Integration offers advantages such as reduced reagent consumption, sample processing, high throughput, and short analysis times.

Conclusions:

  • The combination of quantum dots and microfluidic systems presents a powerful platform for advanced biosensing.
  • This integrated approach significantly enhances bioassay design, offering improved sensitivity and speed.
  • QD-based microfluidic biosensors demonstrate versatility and potential for numerous applications in diagnostics and research.