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Detection of Extravascular Trypanosoma Parasites by Fine Needle Aspiration
Published on: August 7, 2019
Fine needle aspirations in oncology.
A Berner1, M Lund-Iversen, J M Nesland
1Department of Pathology, The Norwegian Radium Hospital, Norway.
Arkhiv Patologii
|December 15, 2011
Summary
Fine needle aspiration cytology (FNAC) is a minimally invasive, accurate, and cost-effective diagnostic method for various organs. Its high accuracy and minimal patient discomfort have overcome clinical skepticism, making it a valuable tool.
Area of Science:
- Medical diagnostics
- Cytopathology
Background:
- Fine needle aspiration cytology (FNAC) is a widely used diagnostic technique.
- It is recognized for its accuracy, cost-effectiveness, and minimally invasive nature.
- Historically, clinician skepticism has decreased due to its proven efficacy and patient tolerance.
Purpose of the Study:
- To highlight the diagnostic utility and applications of FNAC.
- To discuss factors influencing FNAC accuracy.
- To emphasize the integration of advanced techniques with FNAC.
Main Methods:
- FNAC involves obtaining tissue samples from superficial and deep-seated lesions.
- Guidance techniques include palpation and increasingly, ultrasonography.
- Samples are suitable for immunocytochemistry and molecular analyses (PCR, FISH, flow cytometry, cytogenetics).
Main Results:
- FNAC demonstrates high diagnostic accuracy across various organs like breast, lung, thyroid, and lymph nodes.
- Accuracy is influenced by lesion characteristics, aspirator expertise, sample quality, and cytopathologist skill.
- Image guidance (radiography, endoscopy) enhances FNAC for deep-seated lesions.
Conclusions:
- FNAC is a reliable, minimally invasive diagnostic procedure.
- Its accuracy is dependent on multiple technical and expertise-related factors.
- FNAC facilitates advanced molecular and immunocytochemical analyses for comprehensive diagnosis.
