Surgical management of pyogenic liver abscess

A Onder1, M Kapan, A Böyük

  • 1Department of General Surgery, School of Medicine, Dicle University, Diyarbakir, Turkey. draonder@gmail.com

Abstract

Insights

Surgical drainage is effective for complex pyogenic liver abscess (PLA) cases. This study analyzed 28 PLA patients, showing surgical treatment led to a low mortality rate of 7.1%.

Area of Science:

  • Hepatology
  • Surgical Gastroenterology
  • Infectious Diseases

Background:

  • Pyogenic liver abscess (PLA) remains a potentially fatal condition despite advances in antibiotics and intensive care.
  • Early diagnosis and effective treatment are crucial for improving patient outcomes.

Purpose of the Study:

  • To examine surgical treatment methods for pyogenic liver abscess (PLA).
  • To analyze the hospital's case load and outcomes for PLA patients treated surgically.
  • To compare findings with current literature on PLA management.

Main Methods:

  • Retrospective analysis of 55 PLA patients diagnosed between January 2000 and December 2009.
  • Focus on 28 patients who underwent surgical drainage.
  • Data collected included patient demographics, symptoms, abscess characteristics, treatment indications, complications, and outcomes.

Main Results:

  • The study included 28 patients (67.9% male, 32.1% female) with an average age of 41.07 years.
  • Common symptoms were fever and abdominal pain; 82.1% had single lesions, and 67.9% had abscesses on the right lobe.
  • Surgical treatment was indicated due to inappropriate localization for percutaneous drainage (39.3%), insufficient drainage (21.5%), abscess rupture (21.5%), or multiple lesions (17.7%).
  • Complications included pulmonary issues (5), wound infections (5), and perihepatic collections (2).
  • The average hospital stay was 11.2 days, with a low mortality rate of 7.1% (2 deaths).

Conclusions:

  • Surgical treatment is essential for PLA patients unsuitable for or unresponsive to percutaneous drainage.
  • Indications for surgery include multiple abscess cavities, suspected perforation, and coexisting abdominal pathologies requiring laparotomy.
  • Surgical intervention in complex PLA cases can achieve favorable outcomes with manageable complications.