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Related Concept Videos

Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

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Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

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Chronic Obstructive Pulmonary Disease01:24

Chronic Obstructive Pulmonary Disease

COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
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Microbiological Rapid On-Site Evaluation for Pulmonary Infectious Diseases
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Microbiological Rapid On-Site Evaluation for Pulmonary Infectious Diseases

Published on: March 1, 2024

Pulmonary paracoccidioidomycosis.

Flavio Queiroz-Telles1, Dante L Escuissato

  • 1Division of Infectious Diseases, Department of Public Health, Federal University of Parana, Curitiba-Parana, Brazil. queiroz.telles@uol.com.br

Seminars in Respiratory and Critical Care Medicine
|December 15, 2011
PubMed
Summary
This summary is machine-generated.

Paracoccidioidomycosis, a fungal infection caused by Paracoccidioides brasiliensis, affects millions in Latin America. While treatable, it can lead to long-term respiratory and adrenal complications.

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Area of Science:

  • Mycology
  • Infectious Diseases
  • Epidemiology

Background:

  • Paracoccidioidomycosis is a systemic mycosis caused by the fungus Paracoccidioides brasiliensis.
  • It is endemic in Latin America, primarily affecting rural workers, with an estimated 10 million infected individuals.
  • The infection is often subclinical but can lead to severe chronic disease.

Purpose of the Study:

  • To provide a comprehensive overview of Paracoccidioidomycosis.
  • To highlight diagnostic challenges and treatment options.
  • To emphasize the potential for long-term sequelae.

Main Methods:

  • Review of epidemiological data.
  • Clinical case analysis.
  • Microbiological diagnostic criteria.

Main Results:

  • The primary pulmonary infection is frequently asymptomatic.
  • Clinical manifestations require differentiation from other pulmonary conditions.
  • Effective treatments exist, but fibrotic sequelae are common.

Conclusions:

  • Paracoccidioidomycosis is a significant public health issue in endemic areas and a concern for travelers.
  • Accurate diagnosis relies on integrating epidemiological, clinical, and microbiological findings.
  • Long-term management is crucial to address potential respiratory and adrenal complications.