[Vesicoureteral reflux in children]

Silvio Maringhini1, Giovanni Pavone

  • 1U.O.C. Nefrologia Pediatrica, Ospedale dei Bambini ''G. Di Cristina'' A.R.N.A.S. ''Civico, Di Cristina e Benfratelli'', Palermo, Italy. s.maringhini@ospedalecivicopa.org

Insights

Vesicoureteral reflux (VUR) in children can lead to kidney damage and chronic renal failure. Recent evidence suggests reducing diagnostic and surgical interventions for VUR may be beneficial.

Area of Science:

  • Pediatric Nephrology
  • Urology

Context:

  • Vesicoureteral reflux (VUR) is a common pediatric condition often linked to urinary tract infections and renal scarring.
  • Renal damage from VUR can stem from fetal maldevelopment or childhood infections, potentially causing hypertension, pregnancy complications, and chronic renal failure.
  • Bladder dysfunction can exacerbate VUR and lead to persistent renal scarring.

Purpose:

  • To review the current understanding of vesicoureteral reflux in children.
  • To discuss the implications of VUR on renal health and long-term outcomes.
  • To evaluate the evolving strategies in the diagnosis and management of pediatric VUR.

Summary:

  • VUR is a significant pediatric condition associated with urinary tract infections and potential kidney damage.
  • Management strategies for VUR have shifted, with recent trials indicating a trend towards minimizing diagnostic and surgical procedures.
  • Early diagnosis and appropriate management are crucial to prevent renal damage, but the necessity of aggressive interventions is being re-evaluated.

Impact:

  • Highlights the importance of judicious diagnostic and therapeutic approaches in managing pediatric VUR.
  • Informs clinical practice regarding the re-evaluation of routine investigations and interventions for VUR.
  • Contributes to the ongoing discussion on optimizing outcomes for children with VUR while reducing healthcare burdens.

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