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Neutrophils in multiple sclerosis are characterized by a primed phenotype

Matthias Naegele1, Kati Tillack, Stefanie Reinhardt

  • 1Institute for Neuroimmunology and Clinical MS Research (inims), Center for Molecular Neurobiology Hamburg (ZMNH), University Medical Center-Eppendorf, Falkenried 94, 20251 Hamburg (UKE), Germany.

Journal of Neuroimmunology
|December 16, 2011
PubMed
Summary

Neutrophils in multiple sclerosis patients are more numerous and primed, showing reduced apoptosis and enhanced activation markers. This inappropriate priming may increase infection risks due to the chronic inflammatory environment.

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