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Evaluating Therapeutic and Chemical Toxicity Using Organ-Cultured Porcine Corneas and Epithelial Wound Healing
Published on: January 10, 2025
Acute corneal melt associated with topical bromfenac use
1Department of Ophthalmology, Sri Guru Ram Das Institute of Medical Sciences and Research, Vallah, Amritsar, Punjab, India. pawanprasher@yahoo.com
Eye & Contact Lens
|December 16, 2011
Summary
Excessive use of bromfenac eye drops may cause acute corneal melt, especially in patients with dry eyes. Prompt conservative treatment can lead to complete healing and good visual outcomes.
Area of Science:
- Ophthalmology
- Corneal Diseases
- Ophthalmic Pharmacology
Background:
- Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) commonly used post-ophthalmic surgery.
- NSAIDs can cause ocular surface toxicity, including corneal melt.
- Preexisting ocular surface disorders may increase the risk of complications.

