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Sequential protection-modification method for selective sulfhydryl group derivatization in proteins having more than

A Planas1, J F Kirsch

  • 1Department of Molecular and Cellular Biology, University of California, Berkeley 94720.

Protein Engineering
|July 1, 1990
PubMed
Summary

This study generalizes a method to introduce non-natural amino acids into proteins, enabling precise protein modification even with multiple cysteine residues present. This technique is crucial for advancing protein engineering and drug development.

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