Infrapopliteal arterial occlusive disease in elderly men: a population based study

A Clarà1, J Merino, A Planas

  • 1Vascular Surgery Department, Hospital del Mar, Barcelona, Spain. aclara@imas.imim.es

Insights

Isolated infrapopliteal arterial disease is common in older men and linked to coronary heart disease (CHD). This condition, often asymptomatic, shares risk factors like smoking and diabetes with CHD.

Area of Science:

  • Vascular Medicine
  • Cardiology
  • Epidemiology

Background:

  • Peripheral arterial occlusive disease (PAOD) affects older adults.
  • Infrapopliteal arterial disease is a specific manifestation of PAOD.
  • Understanding its prevalence and associations is crucial for cardiovascular health.

Purpose of the Study:

  • To determine the prevalence of isolated infrapopliteal PAOD in older men.
  • To identify associated cardiovascular risk factors.
  • To investigate the link between isolated infrapopliteal PAOD and coronary heart disease (CHD).

Main Methods:

  • Cross-sectional study of 699 men aged 55-74.
  • Collected data on cardiovascular history and risk factors.
  • Utilized electrocardiogram and lower limb segmental pressures/waveforms.

Main Results:

  • PAOD found in 13.4% of subjects; 39.4% had isolated infrapopliteal PAOD.
  • Isolated infrapopliteal PAOD associated with older age, smoking, diabetes, and hypertriglyceridemia.
  • Significant association (OR 1.8-3.4) between PAOD and CHD, regardless of PAOD pattern.

Conclusions:

  • Isolated infrapopliteal PAOD is a frequent, often asymptomatic, condition in older men.
  • It is strongly associated with both symptomatic and asymptomatic CHD.
  • Risk factor profile differs from extended PAOD, primarily in smoking and lipid profile.
Abstract

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